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Analytical Services

Lab testing services, just as its name implies, including some routine chemical and physical analytical measures, are quick and convenient. Nowadays, state-of-the-art technologies and instrumentation along with close collaboration with synthetic organic chemists ensure the highest quality project execution. We solve the most difficult problems by asking the right questions and using the right tools.

Our available analytical services Structure elucidation service: deciphering the structure of complex compounds Physical & Chemical Characterization: extracting intrinsic properties from the chemicals provided Chiral resolution: getting a single chiral enantiomer that is beneficial to the human body and the environment. Identity confirmation: getting purity and structure information Analytical testing laboratories: measure the properties of materials and the fundamental performance of components Impurity profiling: identifying impurities or degradation products

Our Testing Advantages Fast speed, high efficiency, expedited testing Economical preference, save the testing budget for customers Strong technical force, the team has accumulated many years of testing experience Rigorous and accurate data analysis report Wide detection field

Our available analytical techniques

Nuclear Magnetic Resonance (NMR) Nuclear Magnetic Resonance is especially important in the structural analysis of organic compounds. Our Bruker 500 MHz, 400 MHz and 300 MHz Ultra-shield solution state spectrometers are capable of detecting 1H, 13C, 19F and 31P nuclei and are also capable of performing a suite of two-dimensional techniques for the structural elucidation/confirmation of your compounds. Due to the direct correlation between the number of nuclei present and peak areas, qNMR could be used for the quantitation of organic compounds, for assay determination of the material, quantification of impurities and solvents and analysis of enantiomers/stereoisomers ratios.

Chromatography and Mass Spectrometry (MS) Chromatography is a technique to separate mixtures. Using different mobile phases and stationary phases, mixtures could be separated, identified and quantified. Detectors could be selected to capture signals of different categories of compounds. Peak areas are used to calculate the ratios of each ingredient.

High-performance liquid chromatography (HPLC), gas chromatography (GC), supercritical fluid chromatography (SFC), dynamic axial compression chromatography (DAC) HPLC-AgilentHPLC Agilent

Mass spectrometry (MS) works by ionizing chemical compounds to generate charged molecules or molecule fragments and measuring their mass-to-charge ratios. The spectra are used to determine the elemental or isotopic signature of a sample with the mass peaks of particles and molecules, therefore elucidating the fragment information of molecules. MS is very important for confirming the identity of a target molecule. Combining Chromatography and Mass Spectrometry can expand the sample selection and benefit both purposes. For submitted samples, the ingredients could be separated, quantified and identified simultaneously.

X-Ray Crystallography X-Ray Diffraction (XRD) is a useful tool for identifying the atomic and molecular structure of a crystal, in which the crystalline atoms cause a beam of incident X-rays to diffract into many specific directions. By measuring the intensities and angles of these diffracted beams, a crystallographer is capable of producing a 3D picture of the electron density within the crystal. From this electron density, the positions of the atoms in the crystal can be determined, as well as the chemical bonds, the disorder and various other information. X-Ray Powder Diffraction (XRPD) is a rapid analytical technique primarily used for phase identification of a crystalline material and can provide information on unit cell dimensions.

X-ray single-crystal diffraction X-ray powder diffraction

Other General Testing Techniques Infrared Spectroscopy (IR) IR is widely used to analyze and identify substances, and study the interactions and functional groups within and between molecules. The most commonly used is Fourier Transform Infrared Spectroscopy (FTIR).

UV-Vis Absorption Spectroscopy The substance absorbs ultraviolet and visible light and produces the ultraviolet-visible spectrum. According to the absorption degree of the spectrum, the composition, content and structure of the substance are analyzed, measured and inferred.

Polarimeter By measuring the optical rotation of the sample, the polarimeter can analyze and determine the concentration, content and purity of the substance.

Karl Fischer Titrator Karl Fischer titrator is used to determine the trace moisture content in substances.

Element analyzer The element analyzer can realize the analysis of several elements in the sample at the same time or separately.

Our Testing Workflow Customers send us the samples Initial inspection Quotation Sign the contract and start the experiment Complete test Provide test reports, after-sales service

BOC Sciences can provide general test services of high quality and fast turnaround time. With strong scientific knowledge and experience in the regulatory requirements of both the international and domestic industry markets, the analytical development group at BOC Sciences has evolved to interleave with drug discovery, pharmaceutical development and manufacturing.

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